Cd19 B Cells Normal Range

Reference range s see laboratory report.

Cd19 b cells normal range.

The cd19 antigen plays an important role in clinical oncology. It s a protein found on the surface of b cells a type of white blood cell. Cd19 is expressed on all normal mitogen stimulated and malignant b cells excluding plasma cells. Results can indicate a normal cell count or an abnormal cell count the latter pointing to the possible.

Pediatric normal range chart. 21 67 along with t cell maturation activation and co stimulatory molecules in healthy multiracial. Adult normal range chart. Cd19 is a biomarker for b cell development lymphoma diagnosis and therapy.

Cd19 6 3 20 0 cd16 56 3 2 23 7 ratio 1 0 3 6 absolutes 18 yrs cd3 678 2504 cd3 4 414 1679 cd3 8 162 1038 cd19 96 515 cd16 56 45 523 lymphocyte subset normal range chart. The percentages of b cells were evaluated with the expression of cd10 cd19 and cd20. Cd19 expression is even maintained in b lineage cells that undergo neoplastic transformation. Because of its ubiquity on all b cells it can function as a b cell marker and a target for immunotherapies targeting neoplastic lymphocytes.

The b and t cell screen will give an estimate of the amount of t and b cells in the blood. Cd19 is a biomarker for normal and neoplastic b cells as well as follicular dendritic cells. Shearer wt et al. The distribution of these b cell subsets reference ranges based on gender is shown in table 3.

12 18 and 100 adults age range. This manuscript reports on the frequency of cd19 cd5 b cells in normal peripheral blood and confirms the combinations recommended by the european research initiative on cll as being performing to assess remaining cll cells above a threshold of 4 10 4 white blood cells. Reference ranges for cd10 cd19 and cd20 were found to be 1 3 median 1 6 23 median 14 and 6 23 median 14 respectively table 2. Lymphocyte subsets in healthy children.

Lymphoma is a group of blood cancers that develop from lymphocytes cd19 plays a large role in regulating b cell growth. Since cd19 is a hallmark of b cells the protein has been used to diagnose cancers that arise from this type of cell notably b cell lymphomas.